We go with people affected by leprosy and other neglected tropical diseases, regardless of their ethnicity, social reputation, gender or beliefs. We rely on the practical care of people in relation to social justice and equality. The positivity rate for cell markers in HHC was correlated with the degree of endemic which ranges from 10% in China (low endemic) to 53% in Brazil (very endemic), which corresponds to previous results 26. In Brazil, intensive transmission of this study continues, as shown by the particularly high rates of leprosy cases in children27. In addition, it has been reported that in the majority of Brazilian states (19 out of 27), 50% of individuals are exposed to high or hyperdedemic infection rates28. The Brazilian community group tested is therefore not without prejudice from Mr. leprae, since these schoolchildren were probably in contact with people infected with Mr. leprae22. However, the cut-off values are adjustable with quantitative signals, measured by the UCP-LFA in the field parameters. This facilitates a progressive approach that can be taken into account for various diagnostic issues (post-exposure prophylaxis, surveillance, classification) with different sensitivity/specificity requirements. Tiwari, A. et al.
Introduction of leprosy prophylaxis after exposure to health systems in India, Nepal and Indonesia: a case study. BMC Health Serv. Res. 17, 684 (2017). Ridley, D. S. – Jopling, W. H. Classification of leprosy by immunity. A five-group system.
Int. J. Lepr. Other Mycobact. 34, 255–273 (1966). Diagnostic tests on M. lepratic infection becomes a useful resource in large screening efforts to identify people who need prophylactic treatment. In a previous study, we showed that the combination of field-friendly LFS UCP for the detection of cell and humorous biomarker leprosy compared to humoral markers increased sensitivity for patient detection in Bangladesh for MB and 36% for PB7 cases. The current study studies the use of similar UCP-FAs in three other cohorts of different fine leprosy, in order to assess their global applicability as a point-of-care test for leprosy based on the combined detection of multiplex biomarker profiles. Interpretations of the presence of leprosy were made based on descriptions in ancient Indian documentary sources (Atharvaveda and Kausika Sutra), Greek and Middle Eastern (Tzaraath) that describe skin ailments.
 In the 1960s, tens of millions of cases of lepers were recorded when bacteria began to develop resistance to Dapson, the most common treatment option at the time.   International (z.B. WHO`s Global Strategy to Reduce the Burden of Disease through Leprosy” and National Initiatives (. B for example the International Federation of Anti-Leprosy Associations) have reduced the total number and number of new cases of disease.   Multidrug (TDM) treatment remains highly effective and people are no longer contagious after the first monthly dose.  It is safe and easy to use in field conditions, due to its presentation in calendar pads.  Recidivism rates after treatment remain low.  Resistance has been reported in several countries, although the number of cases is small.
 People with rifampicin-resistant leprosy may be treated with second-line medications such as fluoroquinolones, minocycline or clarithromycin, but the duration of treatment is 24 months due to their lower bactericidal activity.  There is still no evidence of the potential usefulness and damage caused by other treatments for drug-resistant leprosy.  The word “leprosy” comes from the Greek word “lepos” – “skin” and “Leper” — drowsy man.